The Reciprocating Dry Powder Aerosol Generation System uses a pneumatic driven device that can be operated in continuous or single puff configurations. A slide bar is actuated into fill, load, and dispersion positions. The actuation rate, volumetric airflows and pressures are set and monitored using a differential pressure orifice meter and a LabVIEW™-based Control Platform.
Advances in pharmaceutical powder technologies have resulted in the increased interest in efficient laboratory scale dry powder aerosol generation devices for research purposes. The Reciprocating Dry Powder Aerosol Generation System was designed to deliver precise qualities of test article directly into the lung in single or multiple breaths. Dry powder aerosols are delivered through the endotracheal tube of the intubated test system. An automated safety “kick-out loop” is built into the system to protect against over-pressurization. Additionally, the Reciprocating Dry Powder Aerosol Generation System can be integrated with any of our in vivo inhalation exposure technologies and in vitro aerosol inhalation exposure systems.